Dotmatics vs Signals Notebook Comparison: Everything You Need to Know Before Choosing

Signals Notebook is a cloud-based electronic laboratory notebook developed by Revvity Signals Software, the scientific informatics business that emerged from PerkinElmer Informatics. The product is designed to help research and development scientists capture, organise, share and explore experimental data in a secure, collaborative environment. It addresses the limitations of paper notebooks and early electronic notebooks, which often served merely as digital paper, making it difficult to search, reuse and analyse data across projects. Signals Notebook approaches this by combining flexible documentation with structured data capture and scientific intelligence, allowing scientists to record experiments in ways that suit their discipline while ensuring that data is standardised and findable for colleagues and downstream analysis. Its cloud-native design reduces infrastructure requirements and supports collaboration across sites and partner organisations. Key features include experiment templates for chemistry, biology, formulations and analytical workflows, with chemical drawing powered by ChemDraw integration, stoichiometry tables and reaction management for chemists. Biologists can record samples, plate layouts and assay data, while structured tables and material management help link experiments to reagents and results. Instrument data and files can be attached and parsed, and search functions allow users to find experiments by text, structure, material or metadata. Collaboration features support sharing, commenting, witnessing and electronic signatures, with audit trails that help meet intellectual property and regulatory requirements. Signals Notebook integrates with the broader Revvity Signals platform, including Signals Inventa for data analytics and Signals Inventory, and connects to third-party systems through APIs. Configuration options allow organisations to adapt templates and workflows without extensive coding. The product is aimed at pharmaceutical and biotechnology companies, chemical and materials science organisations, contract research organisations and academic research groups, from small start-ups to global enterprises. Pricing is quote-based and not published in this listing, and no free trial or free version details are provided.